Some chemical raw materials or products used in pharmaceutical synthesis process
*The following content is generated by AI and is for reference only.
Overview
Oxolan-3-amine hydrochloride is a chiral heterocyclic amine salt widely utilized in pharmaceutical synthesis. Its core production involves the ring-closure of 4-amino-1-butanol followed by hydrochloridation. The compound features the molecular formula C5H12ClNO and carries CAS number 6907-58-8.
Application
- Medicinal Chemistry: Serves as a critical chiral building block for constructing beta-blockers and antihypertensive agents.
- Process Research: Employed in solid-phase synthesis protocols for peptidomimetic drug discovery.
- Quality Control: Used as a reference standard in HPLC analysis for purity verification of active pharmaceutical ingredients.
Precautions
- Storage: Maintain in sealed containers under inert atmosphere at 2-8°C to prevent hydrolysis.
- Safety: Handle with appropriate PPE; avoid inhalation of dust or direct skin contact due to corrosive nature.
- Regulatory: Intended strictly for industrial R&D use, not for direct human clinical administration without further derivatization.