Category:
Active Pharmaceutical Ingredients
CAS NO:
937272-79-2
Standard:
In-house Standards,
Oncology Myeloma
Pacritinib is a potent, selective JAK2 inhibitor designed for myelofibrosis patients with thrombocytopenia. Its core synthesis involves complex heterocyclic coupling to ensure high specificity. Molecular Formula: C24H28ClN5O, CAS No.: 1370689-33-0.
Strictly contraindicated in pregnancy due to fetal toxicity. Requires specialized storage below -20°C and handling under inert atmosphere to prevent degradation. Clinical use mandates monitoring of platelet counts and hepatic enzymes.