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Overview
Palovarotene is a selective retinoic acid receptor gamma agonist developed for treating skeletal disorders. Its molecular formula is C24H28O2 with CAS No. 190768-59-9.
Application
- Oncology: Clinical trials for fibrodysplasia ossificans progressiva.
- R&D: Investigational agent for bone formation inhibition.
- Pharmaceutical Manufacturing: Active pharmaceutical ingredient (API) synthesis.
Precautions
Strictly regulated as an investigational drug; requires controlled storage below 25°C. Contraindicated in pregnancy due to teratogenic risks and potential hepatic toxicity.