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Overview
Paritaprevir is a potent hepatitis C virus (HCV) NS3/4A protease inhibitor. Synthesized via advanced chiral catalysis, its molecular formula is C27H29F3N6O5 with CAS No. 1029685-67-7.
Application
- Pharmaceutical manufacturing for fixed-dose combination antiviral therapies.
- Direct-acting antiviral (DAA) regimens targeting chronic HCV genotype 1 infections.
- R&D of novel protease inhibitors in clinical trial phases.
Precautions
Strictly contraindicated with strong CYP3A inducers due to severe efficacy loss. Requires storage below 25°C in dry, light-resistant conditions. Handling mandates PPE to prevent dermal absorption and inhalation risks.