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Overview
Penicillin G Clemizole is a pharmaceutical salt complex formed by reacting Benzylpenicillin (Penicillin G) with Clemizole hydrochloride. This combination enhances stability and bioavailability for specific therapeutic formulations. The core molecular structure consists of C16H20ClN5O4S with CAS number 129-07-7. Industrial synthesis involves controlled crystallization under sterile conditions to ensure high purity grades suitable for parenteral use.
Application
- Antibiotic Therapy: Primary treatment for susceptible bacterial infections including pneumonia, septicemia, and meningitis.
- Veterinary Medicine: Widely utilized in livestock management for treating respiratory and systemic bacterial diseases.
- Research Reagents: Sourced as a standard reference material for microbiological susceptibility testing and stability studies.
Precautions
Strict adherence to aseptic handling protocols is mandatory due to potent allergenic potential. Storage requires sealed containers at temperatures below 25°C in dry environments to prevent hydrolysis. Clinical use is contraindicated for patients with documented penicillin hypersensitivity or severe renal impairment without dosage adjustment.