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Overview
Pioglitazone HCl is a synthetic antidiabetic agent belonging to the thiazolidinedione class. Manufactured via condensation of 5-ethyl-2-pyridone with ethyl 4-chlorobenzoylacetate followed by salt formation, its molecular formula is C19H20ClNO3S (CAS: 116820-73-8).
Application
- Type 2 Diabetes Mellitus management as monotherapy or combination therapy.
- Improvement of insulin sensitivity in peripheral tissues.
- Regulation of lipid profiles in metabolic syndrome patients.
Precautions
Contraindicated in active liver disease and severe heart failure. Store in cool, dry conditions below 25°C. Handle with PPE due to potential reproductive toxicity risks.