Category:
Cardiovascular System Drugs
CAS NO:
121660-11-5
Standard:
ChP,ChP,
Pitavastatin intermediate P-1 is a critical chiral building block for the synthesis of pitavastatin calcium, a potent HMG-CoA reductase inhibitor. The core process involves asymmetric hydrogenation or resolution to ensure high optical purity. Its molecular formula is C25H26F2N2O4 with CAS number 197086-35-2.
Store under inert atmosphere at 2-8°C to prevent hydrolysis. Handle with appropriate PPE due to potential skin irritation. Strictly avoid exposure during synthesis to maintain enantiomeric excess required for regulatory compliance.