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Overview
Posaconazole is a broad-spectrum triazole antifungal agent produced via advanced organic synthesis. Its molecular formula is C37H42N8O4, with CAS No. 171228-49-2.
Application
- Infectious disease therapy for invasive aspergillosis and candidemia.
- Prophylaxis in immunocompromised patients undergoing hematopoietic stem cell transplantation.
- Treatment of refractory mucocutaneous candidiasis.
Precautions
Strictly monitor hepatic function due to potential hepatotoxicity. Store at controlled room temperature away from moisture. Avoid use in patients with known hypersensitivity to azoles or severe QT prolongation.