Product Description
Name:(R)-3-AMINO-HEXAHYDRO-1H-AZEPINE
CAS No.:124932-43-0
Assay:97%min
Appearance:Colorless liquid
AI Product Description
*The following content is generated by AI and is for reference only.
(R)-3-Amino-hexahydro-1H-azepine, a chiral organic compound, serves as a valuable building block in medicinal chemistry and pharmaceutical research. Its molecular formula is C6H14N2, reflecting a seven-membered saturated heterocyclic ring containing one nitrogen atom (azepine) with an amino substituent at the third position. The specific stereochemistry denoted by the "(R)" prefix indicates its optical activity, distinguishing it from its enantiomer, which is crucial for biological interactions. While a unique CAS number is often assigned to this specific stereoisomer upon registration, it typically falls under the broader category of azepine derivatives used in drug discovery.
This compound finds significant application in the synthesis of complex pharmacological agents, particularly those targeting the central nervous system. The structural framework of hexahydroazepines mimics certain neurotransmitter motifs, making (R)-3-amino-hexahydro-1H-azepine an ideal precursor for developing agonists or antagonists for receptors such as serotonin, dopamine, or opioid systems. Researchers utilize this chiral amine to construct libraries of compounds aimed at treating neurological disorders, including anxiety, depression, and chronic pain. Furthermore, its primary amine functionality allows for versatile derivatization through acylation, alkylation, or reductive amination, facilitating the creation of diverse molecular architectures with tailored physicochemical properties.
In industrial settings, high-purity batches of this enantiomer are essential for ensuring the efficacy and safety of potential therapeutics, as biological systems often respond differently to distinct stereoisomers. Consequently, rigorous quality control measures are employed during its production to maintain optical purity. Beyond pharmaceuticals, it may also serve as a ligand in biochemical assays or a scaffold in material science applications where specific chiral recognition is required. As a specialized intermediate, (R)-3-amino-hexahydro-1H-azepine represents a critical tool for chemists striving to advance novel drug candidates, bridging the gap between fundamental organic synthesis and clinical therapeutic development. Its role underscores the importance of stereochemistry in modern drug design, highlighting how subtle structural variations can profoundly influence biological outcomes.