Radix Scutellariae P.E.
(Baical Skullcap P.E.)
Botanical Source: Scutellaria baicalensis Georgi
Used Part: Root
Specification: Baicalin 10%-98%
Appearance: yellow brown powder
Test Method: HPLC
Bulk density: 0.35-0.75g/mL
Moisture: <5%
Ash: <5%
Description:
Scutellaria baicalensis (or Baikal skullcap, as opposed to Scutellaria lateriflora, a skullcap native to North America) is a species of flowering plant in the Lamiaceae family. The active ingredient is Baicalin.
Baicalin is an active component of Scutellariae radix extracts. It can cross the blood-brain barrier and distribute in cerebral nuclei. However, its mechanism and the effects on the nuclei where it accumulates remain unclear. We used an HPLC-electrochemical detection method to determine the dopamine in cerebral nuclei after intravenous administration of flavonoids from Scutellariae radix and analyzed the relativity between baicalin and DA in cerebral nuclei. We found that the dopamine system is another target system of brain function which baicalin acts on.
Function:
1. To treat respiratory and gastrointestinal infections, allergic rhinitis, jaundice, viral hepatitis, nephritis, pelvic inflammation, sores or swelling, and fever.
2. Baikal Skullcap Extract is also used orally for scarlet fever, headache, irritability, red eyes, flushed face, seizures, epilepsy, hysteria, nervous tension, and a bitter taste in the mouth.
Application:
1. As pharmaceutical raw materials for clearing heat, anti-inflammation, detumescence and so on, it is mainly used in pharmaceutical field;
2. As products effective ingredients for improving blood circulation and soothing the nerves, it is mainly used in health product industry;
3.As active ingredients of Skin Care Products, it is mainly used in cosmetic industry.
*The following content is generated by AI and is for reference only.
Overview
Radix Scutellariae P.E. is a standardized extract derived from Scutellaria baicalensis roots via ethanol extraction and concentration. It primarily contains flavonoids like baicalin, with the core marker often cited as C21H18O11 (CAS: 15976-40-4 for Baicalin).
Application
- Pharmaceuticals: Formulation of anti-inflammatory and antiviral active pharmaceutical ingredients (APIs).
- Dietary Supplements: Used in immune support and liver health functional products.
- Cosmetics: Incorporated into serums for antioxidant protection and skin soothing.
Precautions
Store in cool, dry conditions below 25°C to prevent degradation. Ensure compliance with local pharmacopoeia standards; high doses may require medical supervision due to potential drug interactions.