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Overview
Raltegravir is a integrase strand transfer inhibitor used in antiretroviral therapy. Its molecular formula is C21H25N7O6S and CAS number is 204892-53-7. Core synthesis involves chiral catalysis and heterocyclic coupling.
Application
- HIV-1 infection management as first-line or salvage therapy.
- Combination regimens with other antiretrovirals for viral suppression.
- Post-exposure prophylaxis (PEP) protocols in clinical settings.
Precautions
Strictly monitor for hypersensitivity reactions and myopathy. Store under controlled conditions between 2°C and 8°C to maintain stability. Avoid exposure to direct sunlight and moisture during handling.