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Overview
Raltitrexed is a quinazoline-based antifolate agent. Its core synthesis involves complex heterocyclic construction. Molecular formula: C20H21N7O5; CAS No: 123349-41-5.
Application
- Oncology: Intravenous administration for advanced colorectal cancer.
- Chemotherapy: Used as monotherapy or in combination regimens.
- Research: Tool compound for thymidylate synthase inhibition studies.
Precautions
Strictly contraindicated in severe renal impairment. Requires hospital-grade handling due to cytotoxicity. Store at controlled room temperature away from light and moisture.