Category:
Intermediates&Fine Chemicals
CAS NO:
937779-29-4
Standard:
ChP,
Ramipril Intermediate refers to key synthetic precursors, typically (2S)-1-[(1R)-2-methyl-1-(3-methylbutyl)propyl]-N-[1-oxo-3-phenylpropyl]propanamide, used in the manufacturing of the ACE inhibitor Ramipril. The core process involves asymmetric synthesis and peptide coupling.
Requires strict storage under inert atmosphere at controlled temperatures. Personnel must utilize PPE to prevent dermal absorption. Contraindicated in patients with history of angioedema or bilateral renal artery stenosis.