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Overview
Ramucirumab is a recombinant human IgG1 monoclonal antibody targeting the VEGFR-2 receptor. It inhibits angiogenesis by blocking ligand binding. Molecular Formula: C6588H10164N1744O2092S44. CAS No.: 850177-29-6.
Application
- Oncology therapy for gastric adenocarcinoma.
- Non-small cell lung cancer (NSCLC) treatment regimens.
- Hepatocellular carcinoma management protocols.
- Metastatic colorectal cancer combination therapies.
Precautions
Contraindicated in patients with active bleeding or recent arterial thromboembolic events. Requires strict cold chain storage at 2°C to 8°C. Administration must be performed under medical supervision due to risks of hemorrhage and gastrointestinal perforation.