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Overview
Retigabine (Ezogabine) is an anticonvulsant drug acting as a potassium channel opener. Its core synthesis involves heterocyclic condensation reactions to achieve high purity API standards. Molecular Formula: C16H20N4O; CAS No.: 209787-53-3.
Application
- Epilepsy management for adjunctive treatment of partial-onset seizures.
- Neurological research targeting KCNQ voltage-gated potassium channels.
- Pharmaceutical formulation development for extended-release tablets.
Precautions
Strictly monitor for skin pigmentation changes and urinary retention risks. Store in cool, dry conditions away from light to maintain chemical stability during bulk handling.