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Overview
Ribociclib is a selective cyclin-dependent kinase 4/6 (CDK4/6) inhibitor used in oncology. Its core synthesis involves complex heterocyclic coupling. Molecular Formula: C21H27N5O3; CAS No.: 905487-29-6.
Application
- Hormone receptor-positive, HER2-negative breast cancer treatment.
- Combination therapy with endocrine agents for metastatic disease.
- Advanced clinical trials for solid tumor expansion.
Precautions
Strictly monitor QT interval prolongation and neutropenia risks. Store at controlled room temperature (20-25°C) in moisture-proof containers to maintain stability during distribution.