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Overview
Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in antiretroviral therapy. Synthesized via heterocyclic coupling, its molecular formula is C20H15N5O2 with CAS No. 500785-76-6.
Application
- HIV-1 treatment in combination with other antiretrovirals
- Post-exposure prophylaxis for specific viral strains
- Pharmaceutical manufacturing of fixed-dose combination tablets
Precautions
Contraindicated in patients with baseline viral load >100,000 copies/mL or CD4+ count <200 cells/mm³. Store below 30°C in dry conditions; handle with respiratory protection due to potential sensitization.