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Overview
Rimegepant is a potent calcitonin gene-related peptide (CGRP) receptor antagonist developed for migraine management. Its molecular formula is C27H28N6O4S with CAS number 1952607-95-8. The compound is synthesized via advanced chiral catalysis to ensure high enantiomeric purity.
Application
- Treatment of acute migraine attacks with or without aura.
- Preventive therapy for episodic migraine in clinical settings.
- Pharmaceutical formulation into orally disintegrating tablets for rapid absorption.
Precautions
Contraindicated in patients with severe hepatic impairment or those taking strong CYP3A4 inhibitors. Store at controlled room temperature below 25°C in moisture-proof containers to maintain stability.