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Overview
Rofecoxib is a selective COX-2 inhibitor formerly used in pharmaceutical manufacturing. Its core synthesis involves specific organic coupling reactions. The chemical formula is C17H14O4S with CAS No. 162011-90-7.
Application
- Pain management for osteoarthritis and acute pain.
- Primary treatment of menstrual pain (dysmenorrhea).
- Research reagent for anti-inflammatory mechanism studies.
Precautions
Withdrawn globally due to cardiovascular risks. Strictly controlled storage required away from moisture. Handling requires PPE to prevent dermal absorption during industrial processing.