Category:
Prophylactic Biological Products
CAS NO:
552292-08-7
Standard:
In-house Standards,
Rolapitant is used for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.
It is in R&D stage.
Rolapitant is a potent, selective neurokinin-1 (NK1) receptor antagonist used in oncology. Its core synthesis involves advanced organic coupling and chiral resolution processes. The compound features the molecular formula C25H28F3N3O2 and carries CAS number 769048-83-7.
Contraindicated in patients taking substrates of CYP3A4 with narrow therapeutic indices. Requires storage in cool, dry conditions away from light to maintain stability and prevent degradation.