Category:
Active Pharmaceutical Ingredients
CAS NO:
552292-08-7
Standard:
In-house Standards,
Rolapitant is a potent, selective neurokinin-1 (NK1) receptor antagonist developed for the prevention of chemotherapy-induced nausea and vomiting. Synthesized via complex organic coupling reactions, its molecular formula is C28H29ClN4O2 with CAS No. 176055-62-2.
Strictly contraindicated in patients with severe hepatic impairment. Requires storage at controlled room temperature (20°C–25°C) away from moisture. Clinical use mandates monitoring for potential QT interval prolongation.