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Overview
Rolipram is a potent and selective PDE4 inhibitor primarily utilized in pharmaceutical research. Its molecular structure is defined by the formula C12H15NO4 with CAS registry number 69807-89-2. Industrial synthesis typically involves complex organic reactions to ensure high purity for downstream development.
Application
- Neuroscience Research: Investigating mechanisms of depression, anxiety, and cognitive enhancement via PDE4 pathway modulation.
- Drug Discovery: Serving as a lead compound for developing novel anti-inflammatory and neuroprotective agents.
- In Vitro Assays: Used in biochemical screening to evaluate enzyme inhibition kinetics and cellular signaling pathways.
Precautions
This substance is strictly for laboratory use only and is not approved for clinical therapy in humans. Storage requires sealed containers at -20°C under inert atmosphere to maintain stability. Personnel must utilize appropriate PPE when handling due to potential toxicity and irritant properties.