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Overview
Rosiglitazone Hydrochloride is a synthetic thiazolidinedione derivative used as an antidiabetic agent. It functions primarily by enhancing insulin sensitivity in peripheral tissues. The compound features the molecular formula C18H20ClN3O3S and carries CAS No. 155976-43-5.
Application
- Pharmaceutical Manufacturing: Serves as a key active pharmaceutical ingredient (API) for treating type 2 diabetes mellitus.
- Research & Development: Utilized in clinical trials to evaluate PPAR-gamma agonist efficacy and metabolic pathways.
- Quality Control: Employed as a reference standard for analytical method validation in drug testing laboratories.
Precautions
Strictly monitor for potential risks of heart failure, hepatic toxicity, and bone fractures. Store under inert atmosphere at controlled room temperature away from moisture. Handling requires appropriate PPE due to potential irritancy.