Category:
Chiral Intermediates
CAS NO:
608141-43-1
Standard:
Ph. Int,
(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine N-acetyl-L -leucine salt
This chiral intermediate, (S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine N-acetyl-L-leucine salt, is a diastereomeric salt formed via resolution of racemic amines using L-leucine. It serves as a critical building block for asymmetric synthesis in pharmaceutical manufacturing.
Store under inert atmosphere at 2-8°C to prevent hydrolysis. Handle with PPE due to potential sensitization; avoid inhalation of dust. Strict adherence to GMP guidelines is required for API production.