Category:
Chiral Intermediates
CAS NO:
848821-58-9
Standard:
In-house Standards,
;Chemical Purity0.98 ;Appearance:yellow viscous liquid ;Molecular Formula:C20H28N2SiMolecular Weight:324.54
(S)-2-(Diphenyl(trimethylsilyloxy)methyl)pyrrolidine is a chiral auxiliary and organocatalyst intermediate. Its molecular formula is C19H25NO2Si, with CAS No. 147686-08-4. Synthesis typically involves silylation of (S)-prolinol derivatives using chlorodiphenylmethylsilane under inert atmosphere.
Store under nitrogen at -20°C to prevent hydrolysis. Use in fume hoods due to potential respiratory irritation; wear appropriate PPE including gloves and goggles during handling.