Category:
Active Pharmaceutical Ingredients
CAS NO:
1038924-61-6
Standard:
In-house Standards,
Heart Disease
Sacubitril is a prodrug of sacubitrilat, a potent inhibitor of neutral endopeptidase (NEP). Its core synthesis involves advanced organic coupling and purification. The chemical formula is C24H27FN6O5 with CAS No. 108984-65-0.
Strictly contraindicated in patients with a history of angioedema. Storage requires controlled temperature below 25°C in a dry, inert atmosphere to maintain stability and prevent hydrolysis.