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Overview
Saracatinib is a potent, oral ATP-competitive inhibitor of Src family kinases (SFKs). Its core synthesis involves advanced heterocyclic coupling. The molecular formula is C21H25N7O2 with CAS No. 648090-36-4.
Application
- Oncology Research: Investigating solid tumors and leukemia via SFK pathway modulation.
- Drug Discovery: Serving as a reference standard for kinase inhibitor screening assays.
- Biotech Manufacturing: Used in GMP-grade API production for clinical trial supplies.
Precautions
Strictly limited to investigational use; not approved for commercial therapy. Store under inert atmosphere at 2–8°C. Handle with PPE due to potential mutagenicity and cytotoxicity.