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Overview
Sekukinumab is a fully human monoclonal antibody targeting IL-17A, produced via recombinant DNA technology in mammalian cell lines. Its molecular formula is C2094H3256N558O658S18, with CAS number 1298533-74-2.
Application
- Dermatology: Treatment of moderate-to-severe plaque psoriasis.
- Rheumatology: Management of active psoriatic arthritis.
- Biopharmaceuticals: Manufacturing of therapeutic biologics for autoimmune disorders.
Precautions
Contraindicated in patients with active infections or hypersensitivity to the drug. Store at 2°C to 8°C in original packaging; do not freeze or shake. Monitor for potential immunogenicity during clinical administration.