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Overview
Semaglutide side chain tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu (CAS 1118767-16-0) is a critical pharmaceutical intermediate for GLP-1 receptor agonists. Synthesized via solid-phase peptide coupling, its molecular formula ensures precise lipidation for enhanced half-life.
Application
- API Manufacturing: Essential building block for semaglutide synthesis in diabetes and obesity therapies.
- Peptide Chemistry: Used as a specialized linker to attach palmitic acid derivatives.
- R&D Facilities: Employed in developing novel long-acting injectable formulations.
Precautions
Store at -20°C under inert atmosphere. Handle with PPE due to potential irritancy; strictly avoid ingestion or inhalation during manufacturing processes.