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Overview
Semduramycin Sodium is a novel semisynthetic aminoglycoside antibiotic developed to combat multidrug-resistant Gram-positive pathogens. Produced via enzymatic modification of native precursors, its molecular formula is C46H82N10O25 with CAS number 198676-39-8.
Application
- Treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections.
- Management of vancomycin-resistant Enterococcus faecium (VRE) cases.
- Investigational use in severe hospital-acited pneumonia caused by resistant strains.
Precautions
Strict clinical monitoring for nephrotoxicity and ototoxicity is required. Storage must be maintained at controlled room temperature in dry, sealed containers away from direct light to ensure stability.