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Overview
Sevelamer hydrochloride is a non-absorbed, cross-linked polymer used to lower serum phosphate. Manufactured via emulsion polymerization of acrylamide and allyl methacrylate followed by quaternization, its molecular formula is (C15H24N2O4)n·HCl with CAS 168773-09-9.
Application
- Dialysis patients for chronic kidney disease management.
- Phosphate binder therapy in hyperphosphatemia treatment.
- Combination therapy with dietary restrictions.
Precautions
Avoid concurrent administration with oral medications due to binding interference. Store in tightly closed containers at controlled room temperature (20-25°C). Ensure patient compliance regarding gastrointestinal safety profiles.