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Overview
Sevelamer Hydrochloride is a non-absorbable phosphate binder synthesized via polymerization of allylamine. It functions by binding dietary phosphorus in the gastrointestinal tract to prevent hyperphosphatemia in chronic kidney disease patients. Its molecular formula is C18H24N2O6·xHCl, and its CAS number is 178271-52-0.
Application
- Dialysis management for end-stage renal disease patients
- Control of serum phosphorus levels without calcium load
- Adjunct therapy in cardiovascular risk reduction protocols
Precautions
Avoid concurrent administration with other oral medications due to potential binding interference. Store in a dry environment below 25°C. Use with caution in patients with bowel obstruction history.