Category:
Chiral Intermediates
CAS NO:
33889-69-9
Standard:
In-house Standards,
Pharmaceutical intermediates
Silicristin is a potent synthetic analog of the natural product silvestrol, designed as a selective inhibitor of eukaryotic translation initiation factor 4E (eIF4E). This small molecule acts as an anti-cancer agent by blocking the cap-dependent translation of oncogenic mRNAs. Its core structure distinguishes it from natural flavonoids through specific chemical modifications to enhance bioavailability and potency.
Strictly for research use only; not approved for clinical administration or human consumption. Handle with appropriate PPE due to potential cytotoxicity. Store under inert atmosphere at -20°C to maintain stability and prevent degradation.