Category:
Chiral Intermediates
CAS NO:
139893-43-9
Standard:
In-house Standards,
/
Simvastatin ammonium salt is the water-soluble ionic form of simvastatin hydroxyl acid, primarily utilized to enhance bioavailability in pharmaceutical formulations. Synthesized via neutralization of the active acid with ammonia, this salt improves stability and dissolution kinetics compared to its free acid counterpart.
Strictly contraindicated in patients with active liver disease or hypersensitivity. Store under inert atmosphere at controlled room temperature (15-25°C) to prevent hydrolysis. Handle with appropriate PPE to avoid inhalation of dust particles.