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Overview
Sitafloxacin is a broad-spectrum fluoroquinolone antibiotic characterized by its unique 7,8-difluoro structure. Its core synthesis involves advanced heterocyclic coupling to achieve high potency against resistant strains. The compound features the molecular formula C19H20F2N4O3 and CAS No. 136525-53-4.
Application
- Treatment of complicated skin and soft tissue infections.
- Management of bacterial vaginosis and pelvic inflammatory disease.
- Combination therapy for multidrug-resistant tuberculosis cases.
Precautions
Strictly avoid use in pediatric patients due to cartilage toxicity risks. Store in a cool, dry place below 25°C protected from light. Personnel must wear appropriate PPE during handling to prevent dermal absorption.