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*The following content is generated by AI and is for reference only.
Overview
Sitagliptin Phosphate Monohydrate is a key pharmaceutical intermediate used in the synthesis of antidiabetic agents. It is produced via chiral resolution and crystallization processes. The chemical formula is C16H20F6N5O8P·H2O with CAS No. 486479-78-1.
Application
- Manufacturing of DPP-4 inhibitors for type 2 diabetes management.
- Active Pharmaceutical Ingredient (API) production for oral tablets.
- Quality control standards for generic drug formulations.
Precautions
Store in sealed containers below 25°C to prevent hydrolysis. Handle with appropriate PPE to avoid inhalation or skin contact. Not for direct clinical use without further formulation.