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Overview
Sofosbuvir is a nucleotide analog NS5B polymerase inhibitor synthesized via enzymatic or chemical routes. Its molecular formula is C22H29N3O10P, and the CAS number is 847953-86-8.
Application
- Hepatology: First-line treatment for chronic Hepatitis C virus (HCV) infection.
- Pharmaceutical Manufacturing: Key active pharmaceutical ingredient (API) in combination therapies.
- Clinical Trials: Extensively utilized in research for novel antiviral regimens.
Precautions
Strictly contraindicated with amiodarone due to severe bradycardia risks. Store under controlled conditions at 20°C–25°C in dry, light-resistant containers to maintain stability.