Sophora flavescens P.E.
Botanical Source: Sophora flavescens Ait.
Used Part: Root
Specification: Matrine 20%-98%
Appearance: White crystalline powder or White crystal
Test Method: HPLC
Bulk density: 0.35-0.75g/mL
Moisture: <5%
Ash: <5%
Description:
Sophora flavescens is a species of plant in the genus Sophora a genus of the Fabaceae family, Its roots contain quinolizidine alkaloids, includying matrine and its oxide.
Matrine is an effective antiarrthymic with an aquinidine-like effect; it slows the heart rate, increases cardiac conduction time and decreases myocardial excitability. It directly inhibited artrial muscle reduced the maximal driving frequency, inhibited arrhythmias induced by aconidine and chloroform-epinephrine.
Function:
1. Treat chronic hepatitis B and chronic hepatitis C,
2. Anti-cancer,
3. Treat Cardiac Diseases,
4. Treat Skin Diseases,
5. Anti-bacterial,
6. Anti-arrhythmic effect,
7. Anti-asthmatic effects,
8. Anti-neoplastic effects,
9. Anti-allergic effects.
Application:
As an active ingredient in Pharmaceuticals.
*The following content is generated by AI and is for reference only.
Overview
Sophora flavescens P.E. is a standardized botanical extract derived from the roots of Sophora flavescens, primarily processed via ethanol extraction to isolate active alkaloids including matrine and oxymatrine. The core molecular formula for matrine is C15H24N2O2 with CAS number 6730-58-9.
Application
- Pharmaceuticals: Used in antiviral formulations targeting hepatitis B and C viruses.
- Agriculture: Employed as a natural biopesticide for controlling insect pests and fungal pathogens.
- Health Supplements: Incorporated into dietary supplements for liver support and anti-inflammatory properties.
Precautions
Strict dosage control is required due to potential hepatotoxicity at high concentrations. Storage must be maintained in cool, dry environments below 25°C to prevent alkaloid degradation. Professional handling protocols are mandatory to avoid skin irritation.