Category:
Chiral Intermediates
CAS NO:
3286-46-2
Standard:
JP,
White or pale yellow crystalline powder
Sulbutiamine is a synthetic, lipophilic derivative of thiamine (Vitamin B1) designed to cross the blood-brain barrier. Manufactured via condensation of thiamine with acetyl groups, its molecular formula is C20H27N4O4S and CAS number is 5968-92-3.
Contraindicated in severe hepatic impairment; requires storage below 25°C in dry conditions. Clinical use mandates strict dosage adherence due to potential side effects including insomnia and anxiety.