Category:
Active Pharmaceutical Ingredients
CAS NO:
NA
Standard:
In-house Standards,
Sulfadoxine and Pyrimethamine tablets represent a fixed-dose antimalarial combination. The core synthesis involves coupling sulfonamide derivatives with pyrimidine structures. Key components include Sulfadoxine (CAS 2447-57-6) and Pyrimethamine (CAS 58-14-0), formulated to inhibit sequential steps in folate synthesis.
Contraindicated in patients with severe sulfa or pyrimethamine hypersensitivity. Avoid use during the first trimester of pregnancy due to teratogenic risks. Store in a cool, dry place below 25°C protected from light to maintain chemical stability.