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Overview
Sulfobutyl Ether Beta-cyclodextrin sodium is a water-soluble derivative of beta-cyclodextrin, synthesized via etherification with 1,4-butanesultone. Its molecular formula is typically represented as C42H60O24·nNa (varies by substitution degree), and its CAS number is 128446-35-5. This anionic polymer acts as a potent solubilizing agent.
Application
- Pharmaceuticals: Enhances bioavailability of poorly soluble drugs in injectables and oral formulations.
- Drug Delivery: Serves as a carrier for targeted delivery systems to reduce systemic toxicity.
- Biotechnology: Stabilizes labile proteins and peptides during storage and processing.
Precautions
Strictly monitor renal function due to potential accumulation in patients with kidney impairment. Store in sealed containers at controlled room temperature to prevent moisture absorption and maintain stability.