Category:
Intermediates&Fine Chemicals
CAS NO:
302331-20-0
Standard:
In-house Standards,
t-Boc-N-Amido-PEG-mesyl is a bifunctional polyethylene glycol derivative featuring a tert-butyloxycarbonyl protected amine and a reactive mesylate group. This compound serves as a critical intermediate in solid-phase peptide synthesis and bioconjugation, enabling precise PEGylation of therapeutic proteins via nucleophilic substitution. The specific molecular formula and CAS number are not universally standardized due to variable PEG chain lengths (n).
Store at -20°C under inert atmosphere to prevent hydrolysis of the mesylate moiety. Handle with appropriate PPE as it may act as an alkylating agent. Not intended for direct clinical use without further purification and formulation.