Category:
Preclinical Research Services
CAS NO:
134590-88-8
Standard:
USP, EP,
Tacrolimus Lactone Isomer (Iso-FK-506) is a structural analog of the immunosuppressant tacrolimus, produced via semi-synthesis or fermentation optimization. It serves as a critical intermediate for developing next-generation macrocyclic compounds with reduced toxicity profiles. Molecular Formula: C47H71NO12; CAS No.: 104987-11-7.
Strictly store under inert atmosphere at -20°C to prevent lactone ring hydrolysis. Handle with appropriate PPE due to potential cytotoxicity. Clinical use requires rigorous dose calibration to avoid nephrotoxicity risks associated with structural isomers.