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Overview
Tasocitinib Citrate is a potent, orally bioavailable JAK1/JAK2 inhibitor salt. Its synthesis involves coupling tasocitinib base with citric acid to enhance solubility and stability. The compound features the molecular formula C24H29N7O·C6H8O7 and CAS number 1590733-55-9.
Application
- Rheumatology: Clinical trials for rheumatoid arthritis management.
- Dermatology: Investigational treatments for psoriasis and alopecia areata.
- Pharmaceutical R&D: Reference standard for kinase inhibition profiling.
Precautions
Strictly limit use to authorized clinical research settings due to potential immunosuppression risks. Store under controlled conditions at 2-8°C in dry, light-resistant containers to prevent degradation.