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Overview
Telaprevir is a potent NS3/4A protease inhibitor developed for antiviral therapy. Its molecular formula is C28H41N5O7 with CAS No. 506958-12-9. The compound is synthesized via complex organic coupling reactions to ensure high stereochemical purity.
Application
- Hepatology: Used in combination regimens for treating chronic Hepatitis C virus (HCV) genotype 1 infection.
- Pharmaceutical Manufacturing: Serves as a key Active Pharmaceutical Ingredient (API) for generic drug production.
- Research: Utilized in biochemical assays for studying viral protease mechanisms.
Precautions
Strictly contraindicated in patients with severe hepatic impairment. Storage requires controlled temperature below 25°C in a dry environment. Clinical use mandates monitoring for skin rash and anemia risks.