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Overview
Telavancin is a synthetic lipoglycopeptide antibiotic derived from vancomycin. It functions by inhibiting cell wall synthesis and disrupting membrane potential in Gram-positive bacteria. Its molecular formula is C62H79N13O24, with CAS number 508998-33-0.
Application
- Infectious Diseases: Treatment of complicated skin and skin structure infections (cSSSI).
- Pneumonia Management: Indicated for hospital-acquired bacterial pneumonia caused by susceptible organisms.
- MRSA Therapy: Effective against methicillin-resistant Staphylococcus aureus strains.
Precautions
- Clinical Restrictions: Contraindicated in pregnancy due to fetal toxicity risks.
- Safety Protocols: Monitor renal function and QT interval during administration.
- Storage: Store lyophilized powder at controlled room temperature away from moisture.