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Overview
Tenofovir Alafenamide Fumarate (TAF) is a prodrug of tenofovir used in antiretroviral therapy. It features enhanced stability and reduced systemic exposure compared to TDF. Molecular Formula: C16H25N7O8P; CAS No.: 195646-10-7.
Application
- HIV Treatment: Combined with other agents for chronic infection management.
- Hepatitis B: Suppression of viral replication in adult patients.
- PrEP: Pre-exposure prophylaxis for high-risk populations.
Precautions
Monitor renal function and bone mineral density during long-term use. Store at controlled room temperature, protected from moisture. Contraindicated in severe hepatic impairment without specialist guidance.