Category:
Active Pharmaceutical Ingredients
CAS NO:
1392275-56-7
Standard:
EP,
Tenofovir fumarate Alafolamine (TAF), an oral nucleoside transcriptase inhibitor developed by Gilead, is another prodrug to Tenofovir dipifurate fumarate (TDF), developed for Hepatitis B virus infection (HBV) and acquired immune syndrome (HIV).
Tenofovir alafenamide hemifumarate (CAS 1350648-79-5) is a prodrug of tenofovir with the molecular formula C20H29N6O8P. It is synthesized via esterification to enhance cellular uptake and stability.
Store below 25°C in dry, sealed containers. Monitor renal function during long-term therapy. Avoid use in patients with severe hepatic impairment without specialist consultation.