Category:
Active Pharmaceutical Ingredients
CAS NO:
59804-37-4
Standard:
In-house Standards,
98.0% ~ 102.0% of Tenofovir Disoprovil Fumarate according to ENTERPRISE standards
Tenofovir Disoproxil Fumarate (TDF) is a prodrug of tenofovir, an acyclic nucleoside phosphonate analogue. Synthesized via esterification of tenofovir with isopropylidene and fumaric acid, its molecular formula is C₁₉H₂₈N₆O₁₀P with CAS No. 147127-20-6.
Contraindicated in patients with severe renal impairment without dose adjustment. Store below 25°C in dry conditions. Monitor renal function and bone mineral density during long-term therapy.