Category:
Intermediates&Fine Chemicals
CAS NO:
147127-20-6
Standard:
In-house Standards,
Tenofovir Disoproxil Fumarate (TDF) is a prodrug of tenofovir, an acyclic nucleoside phosphonate analog. It is synthesized via esterification and fumarate salt formation to enhance oral bioavailability. Molecular formula: C19H30N5O10P·C4H4O4; CAS No.: 147127-20-6.
Contraindicated in patients with severe renal impairment without dose adjustment. Requires storage in cool, dry conditions below 25°C. Strict adherence to dosage prevents bone density loss and nephrotoxicity risks.